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Analysis of Domain-Swapped Oligomers Reveals Local Sequence Preferences and Structural Imprints at the Linker Regions and Swapped Interfaces

BACKGROUND: 3D domain swapping is an oligomerization process in which structural elements get exchanged between subunits. This mechanism grasped interest of many researchers due to its association with neurodegenerative diseases like Alzheimer's disease, spongiform encephalopathy etc. Despite t...

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Detalles Bibliográficos
Autores principales: Shingate, Prashant, Sowdhamini, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407178/
https://www.ncbi.nlm.nih.gov/pubmed/22848353
http://dx.doi.org/10.1371/journal.pone.0039305