Matrix metalloproteinase-2 Promotes αvβ3 Integrin-Mediated Adhesion and Migration of Human Melanoma Cells by Cleaving Fibronectin

BACKGROUND: Matrix metalloproteinase-2 (MMP-2) is a key regulator in the migration of tumor cells. αvβ3 integrin has been reported to play a critical role in cell adhesion and regulate the migration of tumor cells by promoting MMP-2 activation. However, little is known about the effects of MMP-2 on...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiao, Yang, Feng, Xue, Zhan, Yinpeng, Wang, Ruifei, Zheng, Sheng, Liu, Wenguang, Zeng, Xianlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407216/
https://www.ncbi.nlm.nih.gov/pubmed/22848537
http://dx.doi.org/10.1371/journal.pone.0041591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407216/
https://www.ncbi.nlm.nih.gov/pubmed/22848537
http://dx.doi.org/10.1371/journal.pone.0041591

Ejemplares similares