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Matrix metalloproteinase-2 Promotes αvβ3 Integrin-Mediated Adhesion and Migration of Human Melanoma Cells by Cleaving Fibronectin

BACKGROUND: Matrix metalloproteinase-2 (MMP-2) is a key regulator in the migration of tumor cells. αvβ3 integrin has been reported to play a critical role in cell adhesion and regulate the migration of tumor cells by promoting MMP-2 activation. However, little is known about the effects of MMP-2 on...

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Detalles Bibliográficos
Autores principales:	Jiao, Yang, Feng, Xue, Zhan, Yinpeng, Wang, Ruifei, Zheng, Sheng, Liu, Wenguang, Zeng, Xianlu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407216/ https://www.ncbi.nlm.nih.gov/pubmed/22848537 http://dx.doi.org/10.1371/journal.pone.0041591

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