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Influence of Mabs on PrP(Sc) Formation Using In Vitro and Cell-Free Systems
PrP(Sc) is believed to serve as a template for the conversion of PrP(C) to the abnormal isoform. This process requires contact between the two proteins and implies that there may be critical contact sites that are important for conversion. We hypothesized that antibodies binding to either PrP(c)or P...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407222/ https://www.ncbi.nlm.nih.gov/pubmed/22848548 http://dx.doi.org/10.1371/journal.pone.0041626 |