Cargando…

A Homeostatic Model of Neuronal Firing Governed by Feedback Signals from the Extracellular Matrix

Molecules of the extracellular matrix (ECM) can modulate the efficacy of synaptic transmission and neuronal excitability. These mechanisms are crucial for the homeostatic regulation of neuronal firing over extended timescales. In this study, we introduce a simple mathematical model of neuronal spiki...

Descripción completa

Detalles Bibliográficos
Autores principales: Kazantsev, Victor, Gordleeva, Susan, Stasenko, Sergey, Dityatev, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407243/
https://www.ncbi.nlm.nih.gov/pubmed/22848555
http://dx.doi.org/10.1371/journal.pone.0041646