Molecular mechanisms of muscarinic acetylcholine receptor–stimulated increase in cytosolic free Ca(2+) concentration and ERK1/2 activation in the MIN6 pancreatic β-cell line

Muscarinic acetylcholine receptor (mAChR) activation of pancreatic β-cells elevates intracellular Ca(2+) and potentiates glucose-stimulated insulin secretion. In addition, it activates a number of signaling molecules, including ERK1/2, whose activation has been shown to play an important role in reg...

Descripción completa

Detalles Bibliográficos
Autores principales: Selway, Joanne L., Moore, Claire E., Mistry, Rajendra, John Challiss, R. A., Herbert, Terence P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407357/
https://www.ncbi.nlm.nih.gov/pubmed/21833779
http://dx.doi.org/10.1007/s00592-011-0314-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407357/
https://www.ncbi.nlm.nih.gov/pubmed/21833779
http://dx.doi.org/10.1007/s00592-011-0314-9

Ejemplares similares