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Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1

BACKGROUND: Members of the Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) adhesion antigen family are major contributors to the pathogenesis of P. falciparum malaria infections. The PfEMP1-encoding var genes are among the most diverse sequences in nature, but three genes, var1, var2cs...

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Detalles Bibliográficos
Autores principales: Wang, Christian W, Lavstsen, Thomas, Bengtsson, Dominique C, Magistrado, Pamela A, Berger, Sanne S, Marquard, Andrea M, Alifrangis, Michael, Lusingu, John P, Theander, Thor G, Turner, Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407477/
https://www.ncbi.nlm.nih.gov/pubmed/22533832
http://dx.doi.org/10.1186/1475-2875-11-129