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Cholecystokinin receptor-1 mediates the inhibitory effects of exogenous cholecystokinin octapeptide on cellular morphine dependence

BACKGROUND: Cholecystokinin octapeptide (CCK-8), the most potent endogenous anti-opioid peptide, has been shown to regulate the processes of morphine dependence. In our previous study, we found that exogenous CCK-8 attenuated naloxone induced withdrawal symptoms. To investigate the precise effect of...

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Detalles Bibliográficos
Autores principales: Wen, Di, Ma, Chun-ling, Zhang, Ya-jing, Meng, Yan-xin, Ni, Zhi-yu, Li, Shu-jin, Cong, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407485/
https://www.ncbi.nlm.nih.gov/pubmed/22682150
http://dx.doi.org/10.1186/1471-2202-13-63