The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein

BACKGROUND: Anaplastic lymphoma kinase-positive, anaplastic large cell lymphoma (ALK+ ALCL) is a T cell lymphoma defined by the presence of chromosomal translocations involving the ALK tyrosine kinase gene. These translocations generate fusion proteins (e.g. NPM-ALK) with constitutive tyrosine kinas...

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Detalles Bibliográficos
Autores principales: Pearson, Joel D, Mohammed, Zubair, Bacani, Julinor T C, Lai, Raymond, Ingham, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407532/
https://www.ncbi.nlm.nih.gov/pubmed/22681779
http://dx.doi.org/10.1186/1471-2407-12-229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407532/
https://www.ncbi.nlm.nih.gov/pubmed/22681779
http://dx.doi.org/10.1186/1471-2407-12-229

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