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DNA Methylation, Histone Modifications, and Signal Transduction Pathways: A Close Relationship in Malignant Gliomas Pathophysiology

Gliomas are the most common type of primary brain tumor. Although tremendous progress has been achieved in the recent years in the diagnosis and treatment, its molecular etiology remains unknown. In this regard, epigenetics represents a new approach to study the mechanisms that control gene expressi...

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Detalles Bibliográficos
Autores principales: Alelú-Paz, Raúl, Ashour, Nadia, González-Corpas, Ana, Ropero, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407642/
https://www.ncbi.nlm.nih.gov/pubmed/22852080
http://dx.doi.org/10.1155/2012/956958