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Angiogenic Signalling Pathways Altered in Gliomas: Selection Mechanisms for More Aggressive Neoplastic Subpopulations with Invasive Phenotype

The angiogenesis process is a key event for glioma survival, malignancy and growth. The start of angiogenesis is mediated by a cascade of intratumoural events: alteration of the microvasculature network; a hypoxic microenvironment; adaptation of neoplastic cells and synthesis of pro-angiogenic facto...

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Detalles Bibliográficos
Autores principales: Bulnes, Susana, Bengoetxea, Harkaitz, Ortuzar, Naiara, Argandoña, Enrike G., Garcia-Blanco, Álvaro, Rico-Barrio, Irantzu, Lafuente, José V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407647/
https://www.ncbi.nlm.nih.gov/pubmed/22852079
http://dx.doi.org/10.1155/2012/597915