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Intracellular proteolysis of kininogen by malaria parasites promotes release of active kinins

BACKGROUND: The malaria burden remains a major public health concern, especially in sub-Saharan Africa. The complex biology of Plasmodium, the apicomplexan parasite responsible for this disease, challenges efforts to develop new strategies to control the disease. Proteolysis is a fundamental process...

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Detalles Bibliográficos
Autores principales: Bagnaresi, Piero, Barros, Nilana MT, Assis, Diego M, Melo, Pollyana MS, Fonseca, Raphael G, Juliano, Maria A, Pesquero, João B, Juliano, Luiz, Rosenthal, Philip J, Carmona, Adriana K, Gazarini, Marcos L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407703/
https://www.ncbi.nlm.nih.gov/pubmed/22564457
http://dx.doi.org/10.1186/1475-2875-11-156