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Activation of c-jun N-terminal kinase in spinal cord contributes to breast cancer induced bone pain in rats

BACKGROUND: The most frequent pain in patients with metastatic breast and prostate cancer is bone pain, which can be severe and difficult to treat. The mechanisms underlying this pain remain unclear. Here we investigated the role of c-jun N-terminal kinase (JNK) pathway in the spinal cord in cancer-...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Wei, Hu, Shan, Mao-Ying, Qi-Liang, Li, Qian, Yang, Chang-Jiang, Zhang, Hui, Mi, Wen-Li, Wu, Gen-Cheng, Wang, Yan-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407760/
https://www.ncbi.nlm.nih.gov/pubmed/22681856
http://dx.doi.org/10.1186/1756-6606-5-21