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Oxidative stress inhibits axonal transport: implications for neurodegenerative diseases

BACKGROUND: Reactive oxygen species (ROS) released by microglia and other inflammatory cells can cause axonal degeneration. A reduction in axonal transport has also been implicated as a cause of axonal dystrophies and neurodegeneration, but there is a paucity of experimental data concerning the effe...

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Detalles Bibliográficos
Autores principales: Fang, Cheng, Bourdette, Dennis, Banker, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407799/
https://www.ncbi.nlm.nih.gov/pubmed/22709375
http://dx.doi.org/10.1186/1750-1326-7-29