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Bacillus anthracis Edema Factor Substrate Specificity: Evidence for New Modes of Action

Since the isolation of Bacillus anthracis exotoxins in the 1960s, the detrimental activity of edema factor (EF) was considered as adenylyl cyclase activity only. Yet the catalytic site of EF was recently shown to accomplish cyclization of cytidine 5′-triphosphate, uridine 5′-triphosphate and inosine...

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Detalles Bibliográficos
Autores principales: Göttle, Martin, Dove, Stefan, Seifert, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407890/
https://www.ncbi.nlm.nih.gov/pubmed/22852066
http://dx.doi.org/10.3390/toxins4070505