Humanized-Single Domain Antibodies (VH/V(H)H) that Bound Specifically to Naja kaouthia Phospholipase A2 and Neutralized the Enzymatic Activity

Naja kaouthia (monocled cobra) venom contains many isoforms of secreted phospholipase A2 (sPLA(2)). The PLA(2) exerts several pharmacologic and toxic effects in the snake bitten subject, dependent or independent on the enzymatic activity. N. kaouthia venom appeared in two protein profiles, P3 and P5...

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Detalles Bibliográficos
Autores principales: Chavanayarn, Charnwit, Thanongsaksrikul, Jeeraphong, Thueng-in, Kanyarat, Bangphoomi, Kunan, Sookrung, Nitat, Chaicumpa, Wanpen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407892/
https://www.ncbi.nlm.nih.gov/pubmed/22852068
http://dx.doi.org/10.3390/toxins4070554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407892/
https://www.ncbi.nlm.nih.gov/pubmed/22852068
http://dx.doi.org/10.3390/toxins4070554

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