Cargando…
Humanized-Single Domain Antibodies (VH/V(H)H) that Bound Specifically to Naja kaouthia Phospholipase A2 and Neutralized the Enzymatic Activity
Naja kaouthia (monocled cobra) venom contains many isoforms of secreted phospholipase A2 (sPLA(2)). The PLA(2) exerts several pharmacologic and toxic effects in the snake bitten subject, dependent or independent on the enzymatic activity. N. kaouthia venom appeared in two protein profiles, P3 and P5...
Autores principales: | Chavanayarn, Charnwit, Thanongsaksrikul, Jeeraphong, Thueng-in, Kanyarat, Bangphoomi, Kunan, Sookrung, Nitat, Chaicumpa, Wanpen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407892/ https://www.ncbi.nlm.nih.gov/pubmed/22852068 http://dx.doi.org/10.3390/toxins4070554 |
Ejemplares similares
-
Ophiophagus hannah Venom: Proteome, Components Bound by Naja kaouthia Antivenin and Neutralization by N. kaouthia Neurotoxin-Specific Human ScFv
por: Danpaiboon, Witchuda, et al.
Publicado: (2014) -
Cell Penetrable Humanized-VH/V(H)H That Inhibit RNA Dependent RNA Polymerase (NS5B) of HCV
por: Thueng-in, Kanyarat, et al.
Publicado: (2012) -
Human monoclonal ScFv that bind to different functional domains of M2 and inhibit H5N1 influenza virus replication
por: Pissawong, Tippawan, et al.
Publicado: (2013) -
Human Monoclonal scFvs that Neutralize Fribrinogenolytic Activity of Kaouthiagin, a Zinc-Metalloproteinase in Cobra (Naja kaouthia) Venom
por: Khanongnoi, Jirawat, et al.
Publicado: (2018) -
Human single chain-transbodies that bound to domain-I of non-structural protein 5A (NS5A) of hepatitis C virus
por: Glab-ampai, Kittirat, et al.
Publicado: (2017)