Functional Expression in Escherichia coli of the Disulfide-Rich Sea Anemone Peptide APETx2, a Potent Blocker of Acid-Sensing Ion Channel 3

Acid-sensing ion channels (ASICs) are proton-gated sodium channels present in the central and peripheral nervous system of chordates. ASIC3 is highly expressed in sensory neurons and plays an important role in inflammatory and ischemic pain. Thus, specific inhibitors of ASIC3 have the potential to b...

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Detalles Bibliográficos
Autores principales: Anangi, Raveendra, Rash, Lachlan D., Mobli, Mehdi, King, Glenn F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407934/
https://www.ncbi.nlm.nih.gov/pubmed/22851929
http://dx.doi.org/10.3390/md10071605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407934/
https://www.ncbi.nlm.nih.gov/pubmed/22851929
http://dx.doi.org/10.3390/md10071605

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