Cargando…
Repression of miR-142 by p300 and MAPK is required for survival signalling via gp130 during adaptive hypertrophy
An increase in cardiac workload, ultimately resulting in hypertrophy, generates oxidative stress and therefore requires the activation of both survival and growth signal pathways. Here, we wanted to characterize the regulators, targets and mechanistic roles of miR-142, a microRNA (miRNA) negatively...
Autores principales: | Sharma, Salil, Liu, Jing, Wei, Jianqin, Yuan, Huijun, Zhang, Taifang, Bishopric, Nanette H |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407949/ https://www.ncbi.nlm.nih.gov/pubmed/22367739 http://dx.doi.org/10.1002/emmm.201200234 |
Ejemplares similares
-
MicroRNA-20a Constrains p300-Driven Myocardial Angiogenic Transcription by Direct Targeting of p300
por: Shehadeh, Lina A., et al.
Publicado: (2013) -
Bromodomain Inhibition Attenuates the Progression and Sensitizes the Chemosensitivity of Osteosarcoma by Repressing GP130/STAT3 Signaling
por: Jiang, Yafei, et al.
Publicado: (2021) -
CD9 exacerbates pathological cardiac hypertrophy through regulating GP130/STAT3 signaling pathway
por: Li, Yue, et al.
Publicado: (2023) -
The Role of gp130 Cytokines in Tuberculosis
por: Ritter, Kristina, et al.
Publicado: (2020) -
p42/p44-MAPK and PI3K are sufficient for IL-6 family cytokines/gp130 to signal to hypertrophy and survival in cardiomyocytes in the absence of JAK/STAT activation
por: Fahmi, Ahmed, et al.
Publicado: (2013)