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Single-neuron RNA-Seq: technical feasibility and reproducibility

Understanding brain function involves improved knowledge about how the genome specifies such a large diversity of neuronal types. Transcriptome analysis of single neurons has been previously described using gene expression microarrays. Using high-throughput transcriptome sequencing (RNA-Seq), we hav...

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Detalles Bibliográficos
Autores principales: Qiu, Shenfeng, Luo, Shujun, Evgrafov, Oleg, Li, Robin, Schroth, Gary P., Levitt, Pat, Knowles, James A., Wang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407998/
https://www.ncbi.nlm.nih.gov/pubmed/22934102
http://dx.doi.org/10.3389/fgene.2012.00124