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A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts
Cellular reprogramming involves profound alterations in genome-wide gene expression that is precisely controlled by a hypothetical epigenetic code. Small molecules have been shown to artificially induce epigenetic modifications in a sequence independent manner. Recently, we showed that specific DNA...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408130/ https://www.ncbi.nlm.nih.gov/pubmed/22848790 http://dx.doi.org/10.1038/srep00544 |