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A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts

Cellular reprogramming involves profound alterations in genome-wide gene expression that is precisely controlled by a hypothetical epigenetic code. Small molecules have been shown to artificially induce epigenetic modifications in a sequence independent manner. Recently, we showed that specific DNA...

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Detalles Bibliográficos
Autores principales: Pandian, Ganesh N., Nakano, Yusuke, Sato, Shinsuke, Morinaga, Hironobu, Bando, Toshikazu, Nagase, Hiroki, Sugiyama, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408130/
https://www.ncbi.nlm.nih.gov/pubmed/22848790
http://dx.doi.org/10.1038/srep00544