Cargando…
A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts
Cellular reprogramming involves profound alterations in genome-wide gene expression that is precisely controlled by a hypothetical epigenetic code. Small molecules have been shown to artificially induce epigenetic modifications in a sequence independent manner. Recently, we showed that specific DNA...
Autores principales: | Pandian, Ganesh N., Nakano, Yusuke, Sato, Shinsuke, Morinaga, Hironobu, Bando, Toshikazu, Nagase, Hiroki, Sugiyama, Hiroshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408130/ https://www.ncbi.nlm.nih.gov/pubmed/22848790 http://dx.doi.org/10.1038/srep00544 |
Ejemplares similares
-
Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts
por: Pandian, Ganesh N., et al.
Publicado: (2014) -
A synthetic DNA-binding inhibitor of SOX2 guides human induced pluripotent stem cells to differentiate into mesoderm
por: Taniguchi, Junichi, et al.
Publicado: (2017) -
A Multi‐target Small Molecule for Targeted Transcriptional Activation of Therapeutically Significant Nervous System Genes
por: Wei, Yulei, et al.
Publicado: (2016) -
Synthetic DNA-Binding Inhibitor
of HES1 Alters the Notch Signaling Pathway and Induces
Neuronal Differentiation
por: Wei, Yulei, et al.
Publicado: (2018) -
Brief exposure to small molecules allows induction of mouse embryonic fibroblasts into neural crest‐like precursors
por: Takayama, Yuzo, et al.
Publicado: (2017)