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Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics

BACKGROUND: Asthma is a chronic inflammatory airway disease influenced by genetic and environmental factors that affects ~300 million people worldwide, leading to ~250,000 deaths annually. Glucocorticoids (GCs) are well-known therapeutics that are used extensively to suppress airway inflammation in...

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Detalles Bibliográficos
Autores principales: Diez, Diego, Goto, Susumu, Fahy, John V, Erle, David J, Woodruff, Prescott G, Wheelock, Åsa M, Wheelock, Craig E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408345/
https://www.ncbi.nlm.nih.gov/pubmed/22713245
http://dx.doi.org/10.1186/1755-8794-5-27