Over-expression of BMPR-IB reduces the malignancy of glioblastoma cells by upregulation of p21 and p27Kip1

BACKGROUND: In our previous study, we detected decreased expression of phospho-Smad1/5/8 and its upstream signaling molecule, bone morphogenetic protein receptor IB subunit (BMPR-IB), in certain glioblastoma tissues, unlike normal brain tissues. In order to clarify the functional roles and mechanism...

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Detalles Bibliográficos
Autores principales: Liu, Shuang, Yin, Feng, Fan, Wenhong, Wang, Shuwei, Guo, Xin-ru, Zhang, Jian-ning, Tian, Zeng-min, Fan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408360/
https://www.ncbi.nlm.nih.gov/pubmed/22650359
http://dx.doi.org/10.1186/1756-9966-31-52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408360/
https://www.ncbi.nlm.nih.gov/pubmed/22650359
http://dx.doi.org/10.1186/1756-9966-31-52

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