Cargando…

Over-expression of BMPR-IB reduces the malignancy of glioblastoma cells by upregulation of p21 and p27Kip1

BACKGROUND: In our previous study, we detected decreased expression of phospho-Smad1/5/8 and its upstream signaling molecule, bone morphogenetic protein receptor IB subunit (BMPR-IB), in certain glioblastoma tissues, unlike normal brain tissues. In order to clarify the functional roles and mechanism...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Shuang, Yin, Feng, Fan, Wenhong, Wang, Shuwei, Guo, Xin-ru, Zhang, Jian-ning, Tian, Zeng-min, Fan, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408360/ https://www.ncbi.nlm.nih.gov/pubmed/22650359 http://dx.doi.org/10.1186/1756-9966-31-52

Ejemplares similares

PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27(Kip1)
por: Nicholas, Courtney, et al.
Publicado: (2013)

Regulation of p27(Kip1) and p57(Kip2) Functions by Natural Polyphenols
por: Russo, Gian Luigi, et al.
Publicado: (2020)

p27(Kip1) and Ser10-phosphorylated p27(Kip1) in breast cancer: clinical significance and expression
por: Song, Wei, et al.
Publicado: (2015)

Cell cycle exit during bortezomib‐induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s‐upregulated p21(Cip1) and p27(Kip1)
por: Zhang, Dan, et al.
Publicado: (2020)

Expression of cyclin-dependent kinase inhibitor p27kip1 in malignant lymphomas.
por: Oh, Y. H., et al.
Publicado: (2000)

Halofuginone and artemisinin synergistically arrest cancer cells at the G1/G0 phase by upregulating p21(Cip1) and p27(Kip1)
por: Chen, Guoqing, et al.
Publicado: (2016)

p27(kip1): a target for tumor therapies?
por: Nickeleit, Irina, et al.
Publicado: (2007)

p27(Kip1) regulates alpha-synuclein expression
por: Gallastegui, Edurne, et al.
Publicado: (2018)

Role of p27(Kip1) as a transcriptional regulator
por: Bachs, Oriol, et al.
Publicado: (2018)

p27(Kip1) – p(RhoB)lematic in lung cancer
por: Podmirseg, Silvio R, et al.
Publicado: (2019)

A Study on BMPR-IB Genes of Bayanbulak Sheep
por: Zuo, Beiyao, et al.
Publicado: (2013)

lncRNA HCG11 suppresses human osteosarcoma growth through upregulating p27 Kip1
por: Gu, Jie, et al.
Publicado: (2021)

Immunohistochemical Expression of p27(Kip1), p57(Kip2), Cyclin D1, Nestin, and Ki-67 in Ependymoma
por: Iqneibi, Shahad, et al.
Publicado: (2022)

EZH2 Is Associated with Malignant Behavior in Pancreatic IPMN via p27(Kip1) Downregulation
por: Kuroki, Hideyuki, et al.
Publicado: (2014)

miR-222 is upregulated in epithelial ovarian cancer and promotes cell proliferation by downregulating P27(kip1)
por: SUN, CHAOYANG, et al.
Publicado: (2013)

Upregulation of MiR-196a promotes cell proliferation by downregulating p27(kip1) in laryngeal cancer
por: Jin, Cheng, et al.
Publicado: (2016)

p27kip1 at the crossroad between actin and microtubule dynamics
por: Rampioni Vinciguerra, Gian Luca, et al.
Publicado: (2019)

p27(Kip1), an Intrinsically Unstructured Protein with Scaffold Properties
por: Bencivenga, Debora, et al.
Publicado: (2021)

p27(kip1) Modulates the Morphology and Phagocytic Activity of Microglia
por: Beeken, Jolien, et al.
Publicado: (2022)

CPEB1 restrains proliferation of Glioblastoma cells through the regulation of p27(Kip1) mRNA translation
por: Galardi, Silvia, et al.
Publicado: (2016)

p27(Kip1) and p21(Cip1) collaborate in the regulation of transcription by recruiting cyclin–Cdk complexes on the promoters of target genes
por: Orlando, Serena, et al.
Publicado: (2015)

TMIGD1 acts as a tumor suppressor through regulation of p21Cip1/p27Kip1 in renal cancer
por: Meyer, Rosana D., et al.
Publicado: (2017)

Human ribosomal protein S13 promotes gastric cancer growth through down-regulating p27(Kip1)
por: Guo, Xueyan, et al.
Publicado: (2011)

Prognostic role of p27(Kip1) and apoptosis in human breast cancer
por: Wu, J, et al.
Publicado: (1999)

Significance of p27(kip1) as potential biomarker for intracellular oxidative status
por: Quintos, Lesley, et al.
Publicado: (2010)

Discovery of Small Molecules that Inhibit the Disordered Protein, p27(Kip1)
por: Iconaru, Luigi I., et al.
Publicado: (2015)

Akt/p27(kip1) Pathway Is Not Involved in Human Insulinoma Tumorigenesis
por: Díaz, Adriana Graciela, et al.
Publicado: (2018)

p27/Kip1 functions as a tumor suppressor and oncoprotein in osteosarcoma
por: Currier, Arthur W., et al.
Publicado: (2019)

BMPR-IB gene disruption causes severe limb deformities in pigs
por: Yang, Qiang, et al.
Publicado: (2022)

Reduced levels of p15INK4b, p16INK4a, p21cip1 and p27kip1 in pancreatic carcinoma
por: LI, GANG, et al.
Publicado: (2012)

Connexin32 inhibits gastric carcinogenesis through cell cycle arrest and altered expression of p21(Cip1) and p27(Kip1)
por: Jee, Hyang, et al.
Publicado: (2013)

PKCζ-dependent upregulation of p27kip1 contributes to oxidative stress induced retinal pigment epithelial cell multinucleation
por: Rajapakse, Dinusha, et al.
Publicado: (2017)

Status of p53 and p27(KIP1) in Iranian Patients With Oral Squamous Cell Carcinoma
por: Etemad-Moghadam, Shahroo, et al.
Publicado: (2015)

Stat1 Phosphorylation Determines Ras Oncogenicity by Regulating p27(Kip1)
por: Wang, Shuo, et al.
Publicado: (2008)

IL-7 promotes T cell proliferation through destabilization of p27(Kip1)
por: Li, Wen Qing, et al.
Publicado: (2006)

Role of T198 Modification in the Regulation of p27(Kip1) Protein Stability and Function
por: Schiappacassi, Monica, et al.
Publicado: (2011)

Nanog induces suppression of senescence through downregulation of p27(KIP1) expression
por: Münst, Bernhard, et al.
Publicado: (2016)

Genetic characterization of p27(kip1) and stathmin in controlling cell proliferation in vivo
por: Berton, Stefania, et al.
Publicado: (2014)

p27(KIP1) and PTEN cooperate in myeloproliferative neoplasm tumor suppression in mice
por: Shao, Jingchen, et al.
Publicado: (2016)

Cell type-specific effects of p27(KIP1) loss on retinal development
por: Ogawa, Mariko, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_6n0hpnggtkite1mh2k39b42sv8