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Exploring functionally related enzymes using radially distributed properties of active sites around the reacting points of bound ligands

BACKGROUND: Structural genomics approaches, particularly those solving the 3D structures of many proteins with unknown functions, have increased the desire for structure-based function predictions. However, prediction of enzyme function is difficult because one member of a superfamily may catalyze a...

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Detalles Bibliográficos
Autores principales: Ueno, Keisuke, Mineta, Katsuhiko, Ito, Kimihito, Endo, Toshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408369/
https://www.ncbi.nlm.nih.gov/pubmed/22536854
http://dx.doi.org/10.1186/1472-6807-12-5