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Exploring functionally related enzymes using radially distributed properties of active sites around the reacting points of bound ligands
BACKGROUND: Structural genomics approaches, particularly those solving the 3D structures of many proteins with unknown functions, have increased the desire for structure-based function predictions. However, prediction of enzyme function is difficult because one member of a superfamily may catalyze a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408369/ https://www.ncbi.nlm.nih.gov/pubmed/22536854 http://dx.doi.org/10.1186/1472-6807-12-5 |