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Coculture with hematopoietic stem cells protects cardiomyocytes against apoptosis via paracrine activation of AKT

BACKGROUND: Previous experimental studies concluded that stem cells (SC) may exert their beneficial effects on the ischemic heart by paracrine activation of antiapoptotic pathways. In order to identify potential cardioprotective mediators, we performed a systematic analysis of the differential gene...

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Detalles Bibliográficos
Autores principales: Rosenberg, Mark, Lutz, Matthias, Kühl, Constantin, Will, Rainer, Eckstein, Volker, Krebs, Jutta, Katus, Hugo A, Frey, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408384/
https://www.ncbi.nlm.nih.gov/pubmed/22672705
http://dx.doi.org/10.1186/1479-5876-10-115