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AGER -429T/C Is Associated with an Increased Lung Disease Severity in Cystic Fibrosis
The clinical course of cystic fibrosis (CF) varies between patients bearing identical CFTR mutations, suggesting the involvement of modifier genes. We assessed the association of lung disease severity with the variant AGER -429 T/C, coding for RAGE, a pro-inflammatory protein, in CF patients from th...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408394/ https://www.ncbi.nlm.nih.gov/pubmed/22860029 http://dx.doi.org/10.1371/journal.pone.0041913 |