AGER -429T/C Is Associated with an Increased Lung Disease Severity in Cystic Fibrosis

The clinical course of cystic fibrosis (CF) varies between patients bearing identical CFTR mutations, suggesting the involvement of modifier genes. We assessed the association of lung disease severity with the variant AGER -429 T/C, coding for RAGE, a pro-inflammatory protein, in CF patients from th...

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Detalles Bibliográficos
Autores principales: Beucher, Julie, Boëlle, Pierre-Yves, Busson, Pierre-François, Muselet-Charlier, Céline, Clement, Annick, Corvol, Harriet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408394/
https://www.ncbi.nlm.nih.gov/pubmed/22860029
http://dx.doi.org/10.1371/journal.pone.0041913

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