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Grainyhead-like 2 regulates epithelial morphogenesis by establishing functional tight junctions through the organization of a molecular network among claudin3, claudin4, and Rab25

During development, epithelial progenitors establish intercellular junctions, including tight junctions (TJs), and form three-dimensional (3D) tissue structures, which are often associated with luminal structures. Here we identify grainyhead-like 2 (Grhl2) as a transcription factor that regulates th...

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Detalles Bibliográficos
Autores principales: Senga, Kazunori, Mostov, Keith E., Mitaka, Toshihiro, Miyajima, Atsushi, Tanimizu, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408412/
https://www.ncbi.nlm.nih.gov/pubmed/22696678
http://dx.doi.org/10.1091/mbc.E12-02-0097