Cargando…

The clathrin adaptor Dab2 recruits EH domain scaffold proteins to regulate integrin β1 endocytosis

Endocytic adaptor proteins facilitate cargo recruitment and clathrin-coated pit nucleation. The prototypical clathrin adaptor AP2 mediates cargo recruitment, maturation, and scission of the pit by binding cargo, clathrin, and accessory proteins, including the Eps-homology (EH) domain proteins Eps15...

Descripción completa

Detalles Bibliográficos
Autores principales: Teckchandani, Anjali, Mulkearns, Erin E., Randolph, Timothy W., Toida, Natalie, Cooper, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408417/
https://www.ncbi.nlm.nih.gov/pubmed/22648170
http://dx.doi.org/10.1091/mbc.E11-12-1007