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Perturbation-based analysis and modeling of combinatorial regulation in the yeast sulfur assimilation pathway

In yeast, the pathways of sulfur assimilation are combinatorially controlled by five transcriptional regulators (three DNA-binding proteins [Met31p, Met32p, and Cbf1p], an activator [Met4p], and a cofactor [Met28p]) and a ubiquitin ligase subunit (Met30p). This regulatory system exerts combinatorial...

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Detalles Bibliográficos
Autores principales: McIsaac, R. Scott, Petti, Allegra A., Bussemaker, Harmen J., Botstein, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408425/
https://www.ncbi.nlm.nih.gov/pubmed/22696683
http://dx.doi.org/10.1091/mbc.E12-03-0232