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Cocaine Withdrawal Causes Delayed Dysregulation of Stress Genes in the Hippocampus
Relapse, even following an extended period of withdrawal, is a major challenge in substance abuse management. Delayed neurobiological effects of the drug during prolonged withdrawal likely contribute to sustained vulnerability to relapse. Stress is a major trigger of relapse, and the hippocampus reg...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408429/ https://www.ncbi.nlm.nih.gov/pubmed/22860061 http://dx.doi.org/10.1371/journal.pone.0042092 |