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Cocaine Withdrawal Causes Delayed Dysregulation of Stress Genes in the Hippocampus

Relapse, even following an extended period of withdrawal, is a major challenge in substance abuse management. Delayed neurobiological effects of the drug during prolonged withdrawal likely contribute to sustained vulnerability to relapse. Stress is a major trigger of relapse, and the hippocampus reg...

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Detalles Bibliográficos
Autores principales: García-Fuster, M. Julia, Flagel, Shelly B., Mahmood, S. Taha, Watson, Stanley J., Akil, Huda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408429/
https://www.ncbi.nlm.nih.gov/pubmed/22860061
http://dx.doi.org/10.1371/journal.pone.0042092