Selective Cytotoxicity of Amidinopiperidine Based Compounds Towards Burkitt’s Lymphoma Cells Involves Proteasome Inhibition

Serine proteases have proven to be promising pharmacological targets in contemporary drug discovery for cancer treatment. Since azaphenylalanine-based compounds manifest cytotoxic activity, we have selected serine protease inhibitors designed and synthesized in-house with large hydrophobic naphthale...

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Detalles Bibliográficos
Autores principales: Gobec, Martina, Obreza, Ales, Prijatelj, Matevz, Brus, Boris, Gobec, Stanislav, Mlinaric-Rascan, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408433/
https://www.ncbi.nlm.nih.gov/pubmed/22860040
http://dx.doi.org/10.1371/journal.pone.0041961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408433/
https://www.ncbi.nlm.nih.gov/pubmed/22860040
http://dx.doi.org/10.1371/journal.pone.0041961

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