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Downregulation of miR-205 Modulates Cell Susceptibility to Oxidative and Endoplasmic Reticulum Stresses in Renal Tubular Cells

BACKGROUND: Oxidative stress and endoplasmic reticulum (ER) stress play a crucial role in tubular damage in both acute kidney injury (AKI) and chronic kidney disease (CKD). While the pathophysiological contribution of microRNAs (miRNA) to renal damage has also been highlighted, the effect of miRNA o...

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Detalles Bibliográficos
Autores principales: Muratsu-Ikeda, Shiyo, Nangaku, Masaomi, Ikeda, Yoichiro, Tanaka, Tetsuhiro, Wada, Takehiko, Inagi, Reiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408438/
https://www.ncbi.nlm.nih.gov/pubmed/22859986
http://dx.doi.org/10.1371/journal.pone.0041462