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Strategy for Identifying Dendritic Cell-Processed CD4(+) T Cell Epitopes from the HIV Gag p24 Protein

Mass Spectrometry (MS) is becoming a preferred method to identify class I and class II peptides presented on major histocompability complexes (MHC) on antigen presenting cells (APC). We describe a combined computational and MS approach to identify exogenous MHC II peptides presented on mouse spleen...

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Detalles Bibliográficos
Autores principales: Bozzacco, Leonia, Yu, Haiqiang, Dengjel, Jörn, Trumpfheller, Christine, Zebroski, Henry A., Zhang, Nawei, Küttner, Victoria, Ueberheide, Beatrix M., Deng, Haiteng, Chait, Brian T., Steinman, Ralph M., Mojsov, Svetlana, Fenyö, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408443/
https://www.ncbi.nlm.nih.gov/pubmed/22860026
http://dx.doi.org/10.1371/journal.pone.0041897