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MMP-9 Cleaves SP-D and Abrogates Its Innate Immune Functions In Vitro

Possession of a properly functioning innate immune system in the lung is vital to prevent infections due to the ongoing exposure of the lung to pathogens. While mechanisms of pulmonary innate immunity have been well studied, our knowledge of how these systems are altered in disease states, leading t...

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Detalles Bibliográficos
Autores principales: Bratcher, Preston E., Weathington, Nathaniel M., Nick, Heidi J., Jackson, Patricia L., Snelgrove, Robert J., Gaggar, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408449/
https://www.ncbi.nlm.nih.gov/pubmed/22860023
http://dx.doi.org/10.1371/journal.pone.0041881