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Reduced APOBEC3H Variant Anti-Viral Activities Are Associated with Altered RNA Binding Activities

APOBEC3H (A3H) is a member of the APOBEC3 family of proteins with varying activities against retroviruses and retrotransposons. The A3H gene contains several single nucleotide polymorphisms and up to seven haplotypes have been detected in humans. Although variations in anti-viral function among A3H...

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Detalles Bibliográficos
Autores principales: Zhen, Anjie, Du, Juan, Zhou, Xiaohong, Xiong, Yong, Yu, Xiao-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408456/
https://www.ncbi.nlm.nih.gov/pubmed/22859935
http://dx.doi.org/10.1371/journal.pone.0038771