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Subcellular Localization of Iron and Heme Metabolism Related Proteins at Early Stages of Erythrophagocytosis

BACKGROUND: Senescent red blood cells (RBC) are recognized, phagocytosed and cleared by tissue macrophages. During this erythrophagocytosis (EP), RBC are engulfed and processed in special compartments called erythrophagosomes. We previously described that following EP, heme is rapidly degraded throu...

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Detalles Bibliográficos
Autores principales: Delaby, Constance, Rondeau, Christiane, Pouzet, Cécile, Willemetz, Alexandra, Pilard, Nathalie, Desjardins, Michel, Canonne-Hergaux, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408460/
https://www.ncbi.nlm.nih.gov/pubmed/22860081
http://dx.doi.org/10.1371/journal.pone.0042199