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TCA Cycle Defects and Cancer: When Metabolism Tunes Redox State
Inborn defects of the tricarboxylic acid (TCA) cycle enzymes have been known for more than twenty years. Until recently, only recessive mutations were described which, although resulted in severe multisystem syndromes, did not predispose to cancer onset. In the last ten years, a causal role in carci...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408673/ https://www.ncbi.nlm.nih.gov/pubmed/22888353 http://dx.doi.org/10.1155/2012/161837 |