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Inhibition of Breast Tumor Cell Growth by Ectopic Expression of p16/INK4A Via Combined Effects of Cell Cycle Arrest, Senescence and Apoptotic Induction, and Angiogenesis Inhibition
p16-mediated inhibition of cancer cell proliferation and tumor suppression have been studied before,; the common consensus is that p16's cell-cycle arrest function plays a primary role in these actions, with some additional apoptotic induction by p16. However, other effects of p16 that may pote...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Ivyspring International Publisher
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408698/ https://www.ncbi.nlm.nih.gov/pubmed/22866168 http://dx.doi.org/10.7150/jca.4046 |