Evidence for Inhibitory Effects of Flupirtine, a Centrally Acting Analgesic, on Delayed Rectifier K(+) Currents in Motor Neuron-Like Cells

Flupirtine (Flu), a triaminopyridine derivative, is a centrally acting, non-opiate analgesic agent. In this study, effects of Flu on K(+) currents were explored in two types of motor neuron-like cells. Cell exposure to Flu decreased the amplitude of delayed rectifier K(+) current (I (K(DR))) with a...

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Detalles Bibliográficos
Autores principales: Wu, Sheng-Nan, Hsu, Ming-Chun, Liao, Yu-Kai, Wu, Fang-Tzu, Jong, Yuh-Jyh, Lo, Yi-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408763/
https://www.ncbi.nlm.nih.gov/pubmed/22888361
http://dx.doi.org/10.1155/2012/148403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408763/
https://www.ncbi.nlm.nih.gov/pubmed/22888361
http://dx.doi.org/10.1155/2012/148403

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