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Oligodendroglia metabolically support axons and contribute to neurodegeneration

Oligodendroglia support axon survival and function through mechanisms independent of myelination and their dysfunction leads to axon degeneration in several diseases. The cause of this degeneration has not been determined, but lack of energy metabolites such as glucose or lactate has been hypothesiz...

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Detalles Bibliográficos
Autores principales: Lee, Youngjin, Morrison, Brett M., Li, Yun, Lengacher, Sylvain, Farah, Mohamed H., Hoffman, Paul N., Liu, Yiting, Tsingalia, Akivaga, Jin, Lin, Zhang, Ping-Wu, Pellerin, Luc, Magistretti, Pierre J., Rothstein, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408792/
https://www.ncbi.nlm.nih.gov/pubmed/22801498
http://dx.doi.org/10.1038/nature11314