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The Blk pathway functions as a tumor suppressor in chronic myeloid leukemia stem cells

A therapeutic strategy for treating cancer is to target and eradicate cancer stem cells (CSCs) without harming their normal stem cell counterparts. The success of this approach relies on identification of molecular pathways that selectively regulate CSC function. Using BCR-ABL-induced chronic myeloi...

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Detalles Bibliográficos
Autores principales: Zhang, Haojian, Peng, Cong, Hu, Yiguo, Li, Huawei, Sheng, Zhi, Chen, Yaoyu, Sullivan, Con, Cerny, Jan, Hutchinson, Lloyd, Higgins, Anne, Miron, Patricia, Zhang, Xueqing, Brehm, Michael, Li, Dongguang, Green, Michael R., Li, Shaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408839/
https://www.ncbi.nlm.nih.gov/pubmed/22797726
http://dx.doi.org/10.1038/ng.2350