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Regulatory effects of the JAK3/STAT1 pathway on the release of secreted phospholipase A(2)-IIA in microvascular endothelial cells of the injured brain
BACKGROUND: Secreted phospholipase A(2)-IIA (sPLA(2)-IIA) is an inducible enzyme released under several inflammatory conditions. It has been shown that sPLA(2)-IIA is released from rat brain astrocytes after inflammatory stimulus, and lipopolysaccharide (LPS) and nitric oxide (NO) have been implicat...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409030/ https://www.ncbi.nlm.nih.gov/pubmed/22788969 http://dx.doi.org/10.1186/1742-2094-9-170 |