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Decreased MHC I expression in IFN gamma mutant mice alters synaptic elimination in the spinal cord after peripheral injury

BACKGROUND: The histocompatibility complex (MHC) class I expression in the central nervous system (CNS) regulates synaptic plasticity events during development and adult life. Its upregulation may be associated with events such as axotomy, cytokine exposition and changes in neuron electrical activit...

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Detalles Bibliográficos
Autores principales: Victório, Sheila CS, Cartarozzi, Luciana P, Hell, Rafaela CR, Oliveira, Alexandre LR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409034/
https://www.ncbi.nlm.nih.gov/pubmed/22564895
http://dx.doi.org/10.1186/1742-2094-9-88