A data-driven model of a modal gated ion channel: The inositol 1,4,5-trisphosphate receptor in insect Sf9 cells

The inositol 1,4,5-trisphosphate (IP(3)) receptor (IP(3)R) channel is crucial for the generation and modulation of intracellular Ca(2+) signals in animal cells. To gain insight into the complicated ligand regulation of this ubiquitous channel, we constructed a simple quantitative continuous-time Mar...

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Detalles Bibliográficos
Autores principales: Ullah, Ghanim, Daniel Mak, Don-On, Pearson, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409100/
https://www.ncbi.nlm.nih.gov/pubmed/22851676
http://dx.doi.org/10.1085/jgp.201110753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409100/
https://www.ncbi.nlm.nih.gov/pubmed/22851676
http://dx.doi.org/10.1085/jgp.201110753

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