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Regulatory T Cells Enhance Susceptibility to Experimental Trypanosoma Congolense Infection Independent of Mouse Genetic Background

BACKGROUND: BALB/c mice are highly susceptible while C57BL/6 are relatively resistant to experimental Trypanosoma congolense infection. Although regulatory T cells (Tregs) have been shown to regulate the pathogenesis of experimental T. congolense infection, their exact role remains controversial. We...

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Detalles Bibliográficos
Autores principales: Okwor, Ifeoma, Onyilagha, Chukwunonso, Kuriakose, Shiby, Mou, Zhirong, Jia, Ping, Uzonna, Jude E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409116/
https://www.ncbi.nlm.nih.gov/pubmed/22860150
http://dx.doi.org/10.1371/journal.pntd.0001761