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Whole Organism High-Content Screening by Label-Free, Image-Based Bayesian Classification for Parasitic Diseases

Sole reliance on one drug, Praziquantel, for treatment and control of schistosomiasis raises concerns about development of widespread resistance, prompting renewed interest in the discovery of new anthelmintics. To discover new leads we designed an automated label-free, high content-based, high thro...

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Detalles Bibliográficos
Autores principales: Paveley, Ross A., Mansour, Nuha R., Hallyburton, Irene, Bleicher, Leo S., Benn, Alex E., Mikic, Ivana, Guidi, Alessandra, Gilbert, Ian H., Hopkins, Andrew L., Bickle, Quentin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409125/
https://www.ncbi.nlm.nih.gov/pubmed/22860151
http://dx.doi.org/10.1371/journal.pntd.0001762